Polyclonalantibody(hostrabbit).IgGfractionpurifiedbyimmobilizedProteinA.
GeneID:18791
Swiss-Prot/UniProtID:P11214
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| Purity | IgGfraction |
|---|---|
| Source | Rabbitserum |
| MolecularWeight | 160,000 |
| TargetMolecularWeight | 70,000 |
| ExtinctionCoefficient | 1.36 |
| Antigen | Recombinantfulllengthwild-typemouseprotein(Glycosylated). |
| Epitope | RecognisesTissuePlasminogenActivator(tPA) |
| CrossReactivity | Ms,Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Species | Mouse |
| Storage | -70C |
| ShippingConditions | Dryice |
| Expiration | 5yearsfromdelivery |
| Form | Frozenliquid |
| Buffer | 0.05MSodiumPhosphate;0.1MNaCl;1mMEDTA;pH6.6 |
| SampleSize | 1.0mg |
| SampleConcentration | 10.0mg/ml |
| SampleVolume | 0.1ml |
| Applications | ELISA,Immunohistochemistry(frozensections),Immunoprecipitation,WesternBlot |
| GeneName | PLAT |
| GeneID | 18791 |
| UniProtID | P11214 |
1.ZaitsevS,DanielyanK,MurcianoJCet-al.Humancomplementreceptortype1-directedloADIngoftissueplasminogenactivatoroncirculatingerythrocytesforprophylacticfibrinolysis.Blood.2006;108(6):1895-902.doi:10.1182/blood-2005-11-012336–Freetextatpubmed–Pubmedcitation
2.AdhamiF,YuD,YinWet-al.Deleteriouseffectsofplasminogenactivatorsinneonatalcerebralhypoxia-ischemia.Am.J.Pathol.2008;172(6):1704-16.doi:10.2353/ajpath.2008.070979–Freetextatpubmed–Pubmedcitation
3.SundaramJR,ChanES,PooreCPet-al.Cdk5/p25-inducedcytosolicPLA2-mediatedlysophosphatidylcholineproductionregulatesneuroinflammationandtriggersneurodegeneration.J.Neurosci.2012;32(3):1020-34.doi:10.1523/JNEUROSCI.5177-11.2012–Pubmedcitation
4.BiohS,SuhN,KimI,LeeJY.Impactsofagingandamyloid-βdepositiononplasminogenactivatorsandplasminogenactivatorinhibitor-1intheTg2576mousemodelofAlzheimer’sdisease.BrainRes.2015;1597:159-67.–linktoarticle
5.CooperJM,RastogiA,KrizoJA,MintzEM,ProsserRA.Urokinase-typeplasminogenactivatormodulatesmammaliancircadianclockphaseregulationintissue-typeplasminogenactivatorknockoutmice.EurJNeurosci.2016;Linktoarticle
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