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Bertin Pharma/Bavachinin/19376/1 mg

Product Overview:
A pan-PPAR agonist (EC50s = 4.0, 8.1, and 0.74 µM for PPARα, β/δ, and γ, respectively); has synergistic effects when combined with thiazolidinediones or fibrates; lowers glucose and triacylglycerol levels in db/db mice
Bavachinin is a natural flavanone first isolated from seeds of P. corylifolia. It is a pan-PPAR agonist (EC50s = 4.0, 8.1, and 0.74 µM for PPARα, β/δ, and γ, respectively). Bavachinin has synergistic effects when combined with thiazolidinediones or fibrates. It lowers glucose and triacylglycerol levels in db/db mice without inducing weight gain or hepatotoxicity. Bavachinin also has actions that block allergic inflammation, angiogenesis, and Aβ42 aggregation in vitro.

Data:

Size: 1 mg
Shipping: dry ice
Stability: Store at -20 degrees; shelf life 730 days maximum after production
CAS Number: 19879-30-2
Molecular Formula: C21H22O4
SMILES: O=C1C[C@@H](C2=CC=C(O)C=C2)OC3=C1C=C(C/C=C(C)/C)C(OC)=C3
Molecular Weight: 338.4
Formulation: A crystalline solid
Purity: ≥98%
Custom Code: 2907199000
UNSPSC code: 12352100
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