Mediomics/Mouse IgG FRET-PINCER® Assay Kit, 384-well format/MIG1012

Thisassaywasdevelopedforuseina384-wellplateformat.A96-wellformatisalsoavailable.Please inquirewithin.

Mediomics’mouseimmunoglobulinG(mIgG)FRET-PINCER®assaykitcanbeusedtoquantitativelydetecttheconcentrationofmIgGinBIOLOGicalsamples.

ImmunoglobulinG(IgG)isthemostabundantimmunoglobulininserum,anditisabioMarkeroftheadaptiveimmuneresponse.Immunoglobulinlevelscanvarywithhealthstatus,age,anddrugtreatment;therefore,quantitativemeasurementsareausefultoolforpre-clinicalresearchers. Overabundanceor,conversely,anabsenceofacertainspecificsubclassmaybeassociatedwithdisease.

Productapplications:

1.Drugandvaccinetestingtoidentifythepresence/absenceofanadaptiveimmuneresponse.

2.RapiddetectionofIgGantibodiesinapull-downorco-IPassay.

3.DetectionofmIgGconcentrationwithinbiologicalsamplesaspartofapre-clinicalresearchprogram.

ProductAdvantage:

Mediomics’mIgGFRET-PINCER®assayisideallysuitedfortherapid,simultaneousmeasurementofmouseIgGlevelsinlargenumberoftestsamplesduetoitsspeedandsimplicity.ItisreADIlyadaptabletothehigh-throughputscreeningplatformscurrentlybeingusedindrugdiscoveryresearch.

IncomparisontotheELISAprocedure,theFRET-PINCER®technologyprovidesasimple(onemixingstep)andfast(30minuteincubation)assaythatisquantitativeandreproducIBLe.

Fig.1:MouseIgGPINCER®Standardcurve

Fig.2:LinearrangeoftheMouseIgGPINCER®Standardcurve

Note:Thesestandardcurvesareforreferenceonly.Pleasegenerateyourownstandardcurve.

LimitofDetection(LOD):3.9ng/mL

CVvalue:< 7%

DetectionRange:3.9–1000ng/mL

Pricing: The100-wellkitisaone-timetrialpurchase.Forbulkpricingoptions,please contactus.Foranyotherquestionsorcomments,pleasedonothesitateto contactus.Wearealwayshappytohelp!

PleaserefertoourtechnologypagesforinformationonthescientificprinciplesandtechnologicaladvancementsoftheFRET- PINCER®assays.

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1. PINCER®isaregisteredtrademarkofMediomics,LLC,St.Louis,Missouri,U.S.A.Mediomicshasaworldwide,exclusivelicenseforthisassayplatformfromSaintLouisUniversity,St.Louis,Missouri.

2. ThePINCER® AssaykitisprovidedforlaboratoryR&Duseonly.ThisproductisnotapprovedbytheU.S.Governmentorbythegovernmentofanyothercountryoftheworldforuseintheclinicaldiagnosisofdisease,ortreatmentofdiseaseinhumansoranimals.

3. PatentsallowedandpendingintheU.S.andabroad.

4. PINCER®productshavebeendevelopedwithsupport,inpart,fromtheNationalInstitutesofHealth,throughSTTRPhaseIandPhaseIIGrants.

Catalog#:MIG1012-100,MIG1012-384

Protocol: 

MouseIgGPINCERAssayKit,384wellformatprotocol677.53KB

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MSDS: 

MouseIgGPINCER/TRF-PINCERAssayKitSDS204.56KB

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