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ThemouseIL-17AELISAdevelopmentkitisidealforuserswhowanttheflexibilityofsettinguptheirownELISAassay.ThisproductenablesquantificationofmouseIL-17Ainsolution,e.g.incellculturesupernatant.Thekitcontainsamatchedpairofmonoclonalcaptureanddetectionantibodies,Streptavidin-ALPandELISAstandard.Platesandsubstratearenotincluded.
MouseIL-17AELISAdevelopmentkitsarealsoavailablewithStreptavidin-HRP.SeeRelatedproducts.
Ready-to-useELISAsubstrateisavailableinourwebshop.SeeRelatedproducts.
IL-17A
Interleukin-17A(IL-17A,IL17A)isapotentproinflammatorycytokineproducedbyactivatedTh17(T-helper17)cellsandcertaincellsbelongingtotheinnateimmunesystem.Inmice,IL-17hasbeenshowntoalsobeproducedbyactivatedCD8+TcellsandγδTcells.Th17cellsplayanimportantroleinautoimmunediseasesandprotectionagainstbacteriaandfungi.IL-17Aactsonabroadrangeofcelltypestoinduceexpressionofcytokines,chemokinesandmetalloproteinases.Asaresult,secretionofIL-17Apromotesinflammatoryresponses,whichleadstotherecruitmentofneutrophils,enhancementofantibodyproductionandactivationofTcells.IncreasedexpressionofIL-17Aisseeninautoimmunediseasessuchasmultiplesclerosisandrheumatoidarthritis.Itisalsoassociatedwithasthma,psoriasis,cancerandtransplantrejection.
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| Standardrange: | 5-500pg/ml |
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| Size: | for6plates |
| Otherformats: | ClicktoviewallMouseIL-17Aproducts |
| SavetimeandreducevariABIlitywiththe completeandpre-coatedELISpotPLUSkit | |
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