ThismonoclonalantibodyenablessensitiveandspecificdetectionofmouseIgG3ine.g.antigen-specificELISA.
Thereisnocross-reactivity(<0.1%)withmouseIgG1,IgG2a,IgG2b,IgG2c(IgG2aanalogueine.g.C57BL/6andNODmice),IgA,IgE,IgMorwithIgGfromrat,goat,rabbit,cowandhuman.
IgG3
IgG(ImmunoglobulinG)isthemostabundantIgisotypeinserumandmakesupapproximately80%ofallserumImmunoglobulins.Inhumans,therearefoursubclassesofIgGwithhighestserumconcentrationsofIgG1followedbyIgG2,IgG3andIgG4.Inmice,theIgGsubclassesaredefinedIgG1,IgG2a/c,IgG2bandIgG3.IgG3bindstoFcreceptorswithhighaffinityandhasisagoodcomplementactivator.
Application: |
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Reactivity: |
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Format: | Biotinylated |
Specificity: | MouseIgG3 |
Isotype: | RatIgG1 |
Contents: |
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Size: | 250µg |
Otherformats: | ClicktoviewallMouseIgG3products |
VeryeasytouseELISAkit.
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