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TOKU-E/LL-37 (human) trifluoroacetate salt/L046/1 mg

LL-37isanaturally-occuringantimicrobialpeptidethatispartoftheinnatehostimmunesystem.Itisassociatedwiththeepidermisandprotectsthehostfrombacterialinfection.LL-37hasalsodemonstratedarangeofotherbioactivityincludinganti-influenza,immunomodulatory,andcelldeathactivityincertaincelltypes.Unlikeotherantimicrobialpeptides,LL-37canaggregatetoprotectfromproteolyticdegredation.

    CASNumber

    597562-32-8

    MolecularFormula

    C205H340N60O53

    MolecularWeight

    4493.32

    MechanismofAction

    LL-37assumesaprimarilyα-helicalshapeduringmembraneinteractionsallowingformembranepenetration,formationoftransmembraneporesandbacteriallysis.

Specifications:

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