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TOKU-E/Erlotinib hydrochloride/E017/100 mg

Erlotinibhydrochlorideisadrugusedtotreatnon-smallcelllungcancer,pancreaticcancerandseveralothertypesofcancer.Itisatyrosinekinaseinhibitor,whichactsontheepidermalgrowthfactorreceptor(EGFR).

    CASNumber

    183319-69-9

    MolecularFormula

    C22H23N3O4

    MolecularWeight

    393.43

    MechanismofAction

    Erlotinibisanepidermalgrowthfactorreceptor(EGFR)inhibitor.ErlotinibspecificallytargetstheEGFRtyrosinekinaseATPbindingsite,whichishighlyexpressedandoccasionallymutatedinvariousformsofcancer.ErlotinibpreventsEGFRhomodimerformation,aconformationalchangerequiredforsignaltransmittance.

    StorageConditions

    2-8°C

    TariffCode

    2933.59.5300

Specifications:

    Form

    Powder

    Appearance

    Whiteoroff-whitepowder

    Source

    Synthetic

    MeltingPoint

    223-228°C

    Assay

    98.0-101.0%

    LossonDrying

    ≤0.5%

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