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Prospec/ARL15 Human/PRO-956/1mg

Cataloguenumber

PRO-956

Synonyms

ADP-ribosylationfactor-like15,ADP-ribosylationfactorrelatedprotein2,ARFRP2,ARF-relatedprotein2,FLJ20051.

Introduction

ARL15isamemberoftheARFfamilywhichareessentialineukaryoticvesiculartraffickingpathwaysandhaveavitalpartintheactivationofphospholipaseD.ARL15variantsinfluencelevelsofAcrp30,anADIpocyte-derivedproteinthatisextremelygeneticandinverselyrelatedtotheProspectoftype2diabetesmellitusandcoronaryheartdisease.

Description

ARL15HumanRecombinantproducedinE.coliisasingle,non-glycosylatedpolypeptidechaincontaining224aminoacids(1-204)andhavingamolecularmassof25.0kDa.
ARL15isfusedtoa20aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.

Source

E.coli.

PhysicalAppearance

SterileFilteredcolorlesssolution.

Formulation

TheARL15solution(1mg/ml)contains20mMTris-HClbuffer(pH8.0),1mMDTT,0.1MNaCland10%glycerol.

StABIlity

Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.

Purity

Greaterthan85%asdeterminedbySDS-PAGE.

Aminoacidsequence

MGSSHHHHHHSSGLVPRGSHMSDLRITEAFLYMDYLCFRALCCKGPPPARPEYDLVCIGLTGSGKTSLLSKLCSESPDNVVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLEAARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILQPCSLDDMDALKDSFSQLINLLEEKDHEAVRM 

Usage

ProSpec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.
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