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HumanZyme/FGF-10 (Fibroblast Growth Factor-10)/HZ-7158/25 µg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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HumanZyme/FGF-10 (Fibroblast Growth Factor-10)/HZ-7158/25 µg

 ProductDescription:

FGF-10isaheparin-bindinggrowthfactorthatbelongstotheFGFfamily.Proteinsofthisfamilyplayacentralroleduringprenataldevelopment,postnatalgrowthandregenerationofavarietyoftissues,bypromotingcellularproliferationanddifferentiation.FGF-10ismostrelatedtoKGF/FGF-7,andisexpressedduringthedevelopmentand,preferentially,inadultlungs.ItsignalsthroughtheFGFR2b.

TechnicalSpecifications:

  • Species:Human
  • Expression:E.coliCellExpressed
  • Activity:Typically≤0.5ng/mlED50
  • Purity:≥95%
  • Endotoxin:<1.0EU/μg
  • MolecularMass:19.3kDa
  • Formulation:5mMSodiumPhosphatepH7.4+80mMNaCl
  • CountryofOrigin:USA

PurityConfirmation:

ThiswasdeterminedbySDS-PAGEgelandHPLCanalysis.

ActivityAssay:

TheED50asdeterminedbythedose-dependentstimulationofthymidineuptakebyBaF3cellsexpressingFGFreceptorsis≤0.5ng/ml,correspondingtoaspecificactivityof≥2x106units/mg.

AASequence:

MLGQDMVSPEATNSSSSSFSSPSSAGRHVR
SYNHLQGDVRWRKLFSFTKYFLKIEKNGKV
SGTKKENCPYSILEITSVEIGVVAVKAINS
NYYLAMNKKGKLYGSKEFNNDCKLKERIEE
NGYNTYASFNWQHNGRQMYVALNGKGAPRR
GQKTRRKNTSAHFLPMVVHS

ReconstitutionBuffer:

Centrifugethevialpriortoopening.5mMSodiumPhosphate,pH7.4toaconcentrationof0.1-1.0mg/ml.Donotvortex.

Storage:

Forextendedstorage,itisrecommendedtofurtherdiluteinabuffercontainingacarrierprotein(example0.1%HSA)andstoreinworkingaliquotsat-20°Cto-80°C.

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