Xeno-freeIL-23HuXpisexpressedinhuman293cellsasaheterodimericglycoproteincomposedoftwodisulfide-linkedsubunits(p40cystinelinkedtop19).IL-23hasbeenshowntoenhanceproliferationofmemoryTcells.ItalsostimulatestheproductionofIFN-gammainNKcells,inducesIL-17production,anddrivesTh17mediatedresponses.FurThermore,itisknownthatIL-23takesavitalpartintheinflammationprocessandthatitisassociatedwithautoimmunediseases.
TheproteinwasresolvedbySDS-polyacrylamidegelelectrophoresisandthegelwasstainedwithCoomassieblue.
Theactivitywasdeterminedbythedose-dependentsecretionofIL-17inresponsetoIL-23usingmurinesplenocytes.
Brieflycentrifugethevialbeforeopening.Itisrecommendedtoreconstitutetheproteininsterile1xPBScontaining0.1%endotoxin-freerecombinanthumanserumalbumin(HSA).
Jackson/Peroxidase AffiniPure Goat Anti-Mouse IgG (H+L)/2.0 ml/115-035-003
Jackson/Peroxidase AffiniPure Goat Anti-Rabbit IgG (H+L)/2.0 ml/111-035-003
Qubit™ dsDNA BR Assay Kit Q32853现货
Invitrogen Q32855 Qubit™ RNA HS Assay Kit现货促销
LUCK-1G,D-Luciferin, Potassium Salt 钾盐现货
GoldBio/D-Luciferin, Sodium Salt (Proven and Published)/LUCNA-1G/1 g