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HumanZyme/IL-23  (Interleukin 23)/HZ-1261/100 µg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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HumanZyme/IL-23  (Interleukin 23)/HZ-1261/100 µg

ProductDescription:

  • Endotoxin-free
  • Animal-derivedproductfree
  • AvailableinBulk
  • LyophilizedandCarrierFree(CF)
  • Expressedasdisulfide-linkedheterodimer

Xeno-freeIL-23HuXpisexpressedinhuman293cellsasaheterodimericglycoproteincomposedoftwodisulfide-linkedsubunits(p40cystinelinkedtop19).IL-23hasbeenshowntoenhanceproliferationofmemoryTcells.ItalsostimulatestheproductionofIFN-gammainNKcells,inducesIL-17production,anddrivesTh17mediatedresponses.FurThermore,itisknownthatIL-23takesavitalpartintheinflammationprocessandthatitisassociatedwithautoimmunediseases.

TechnicalSpecifications:

  • Species:Human
  • Expression:HEK293CellExpressed
  • Activity:Typically≤30ng/mLEC50
  • Purity:>95%
  • Endotoxin:<1EU/µg
  • MolecularMass:55kDa,heterodimer,glycosylated
  • Formulation:1xPBS

PurityConfirmation:

TheproteinwasresolvedbySDS-polyacrylamidegelelectrophoresisandthegelwasstainedwithCoomassieblue.

ActivityAssay:

Theactivitywasdeterminedbythedose-dependentsecretionofIL-17inresponsetoIL-23usingmurinesplenocytes.

ReconstitutionBuffer:

Brieflycentrifugethevialbeforeopening.Itisrecommendedtoreconstitutetheproteininsterile1xPBScontaining0.1%endotoxin-freerecombinanthumanserumalbumin(HSA).

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